Smoking is the leading cause of death for both men and women in the United States. About 420,000 deaths occur each year as a result of smoking cigarettes. Individuals who smoke are likely to develop peptic ulcer disease, and are more likely to develop cataracts, as opposed to non-smokers. People, who smoke, are ten times more likely to die from larynx cancer, esophagus, chronic obstructive lung disease, including emphysema. The risk becomes even higher if cigarette smoking is combined with alcohol use or with occupational exposure to certain types of toxic substances, such as asbestos.