Watch the Splice Trailer. Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named ‘Dren’, the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators – only to have that bond turn deadly. Watch the Splice preview in 480p or 720p streaming online. Break.com delivers official movie trailers previews, teasers and clips in HD for all the hottest coming soon & theatrical releases including the Sci Fi/Fantasy Splice.